Betamethasone Sodium Phosphate is used for the treatment of several allergic disorders including angioedema, severe rhinitis, serum sickness, acute noninfectious laryngeal edema and also urticarial transfusions reactions. It is effective against collagen disorders like carditis (rheumatic or nonrheumatic), polyarteritis nodosa, systemic lupus erythematosus. It is useful in skin disorders like atopic dermatitis, exfoliative dermatitis, severe multiforme erythema herpetiformis, granuloma annulare, lichen simplex chronicus, bullous dermatitis, seborrheic dermatitis, severe psoriasis. It is also used in endocrine disorders like Addison’s disease, Cushing’s syndrome, acute adrenocortical insufficiency and also gastrointestinal disorders like Crohn’s disease, ulcerative colitis. It is effectively used in many hematologic, neurologic, respiratory, neoplastic and rheumatic disorders.