CHLOROQUINE DIPHOSPHATE is used in the treatment of chronic malaria attacks caused by Plasmodium malariae, Plasmodium falciparum, Plasmodium ovale and Plasmodium vivax. It is effective in amebic liver abscess, juvenile arthritis, chronic rheumatoid arthritis and reducing urinary calcium excretion. It acts as a suppressant in polymorphous light eruption and systemic lupus erythematosus.