ZIZIPHI SPINOSAE EXTRACT 6-1 is obtained from the plant Zizyphus sativa which has concentration dependent impacts on apoptosis and differential cell cycle arrest. It is effective to treat neonatal jaundice. It also exhibits antimicrobial activity and is used to treat microbial infections especially in children. When used in conjunction with green tea extract, it enhances the cytotoxic activity in HepG2 cells. It is also effective against diabetes induced abnormalities.